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Reserch Articles

Lu SL, Kawabata T, Cheng YL, Omori H, Hamasaki M, Kusaba T, Iwamoto R, Arimoto H, Noda T, Lin YS, Yoshimori T*.

Endothelial cells are intrinsically defective in xenophagy of Streptococcus pyogenes.
PLoS Pathog. 13, e1006444. (2017)

PubMed

Sasai M, Sakaguchi N, Ma J, Nakamura S, Kawabata T, Bando1 H, L Youngae, Saitoh T, Akira S, Iwasaki A, Standley D, Yoshimori T, Yamamoto M*.

Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense.
Nat Immunol.18(8):899-910. (2017)

PubMed

Hori I, Otomo T, Nakashima M, Miya F, Negishi Y, Shiraishi H, Nonoda Y, Magara S, Tohyama J, Okamoto N, Kumagai T, Shimoda K, Yukitake Y, Kajikawa D, Morio T, Hattori A, Nakagawa M, Ando N, Nishino I, Kato M, Tsunoda T, Saitsu H, Kanemura Y, Yamasaki M, Kosaki K, Matsumoto N, Yoshimori T, Saitoh S*.

Defects in autophagosome-lysosome fusion underlie Vici syndrome, a neurodevelopmental disorder with multisystem involvement.
Sci Rep. 7, 3552. (2017) doi: 10.1038/s41598-017-02840-8.

PubMed

Hubber A, Kubori T, Coban C, Matsuzawa T, Ogawa M, Kawabata T, Yoshimori T, Nagai H*.

Bacterial secretion system skews the fate of Legionella-containing vacuoles towards LC3-associated phagocytosis.
Sci Rep. 7, 44795. (2017) doi: 10.1038/srep44795.

PubMed

Takahashi A, Takabatake Y*, Kimura T, Maejima I, Namba T, Yamamoto T, Matsuda J, Minami S, Kaimori JY, Matsui I, Matsusaka T, Niimura F, Yoshimori T, Isaka Y.

Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules.
Diabetes. 66, 1359-1372. (2017) Epub 2017 Feb 28.

PubMed

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